PEG linkers are widely used in peptide synthesis, bioconjugation and drug development. Their hydrophilic and flexible nature improve solubility, provide molecular spacing and help reduce aggregation and steric interactions. PEGylation can be used to modify the properties of peptide therapeutics, including their stability and circulation behaviour. (Ma et al., 2025) Not all PEGs are made … Read more
Erik Agner, CEO Polypure AS The COVID-19 pandemic created a demand for a fast response to provide vaccines to a concerned world population. In this post, we will describe how Polypure developed monodisperse, heterobifunctional PEGs of higher molecular weights for advanced pharmaceutical applications based on the COVID-19 vaccine R&D project. The technology of mRNA incorporated … Read more
Monodisperse PPG may offer distinct advantages — particularly for hydrophobic drug delivery.
At Polypure we developed a monodisperse PPG.
In our recent article published on the prestigious Chemistry World website, we explore how monodisperse PEG from Polypure, with a defined and uniform molecular weight, enables a higher level of precision in drug development and bioconjugation. By eliminating molecular heterogeneity, monodisperse PEG supports more reliable characterisation, improved process control, and more consistent outcomes across research … Read more
Polypure AS – the PEG specialist – is visiting CPHI Frankfurt 2025 on 28th-30th October. We are there to discover, connect and upskill! Will we see you there? Contact us at info@polypure.no to arrange a meeting!
Polypure has recently expanded its offer in 2 kDa PEGs. Our catalogue is now updated and a list of 2 kDa products can be found here: https://polypure.com/product-list/peg-2000/
On Thursday 3rd July 2025, our colleague Yomkippur Perez defended her Ph.D. thesis at the University of Stavanger entitled “Monodisperse Poly(ethylene glycol) Derivatives for Pharmaceutical Applications”.