In this article, published in the prestigious Chemistry World website, we explore how monodisperse PEG from Polypure, with a defined and uniform molecular weight, enables a higher level of precision in drug development and bioconjugation. By eliminating molecular heterogeneity, monodisperse PEG supports more reliable characterisation, improved process control, and more consistent outcomes across research and pharmaceutical applications.
Poly(ethylene glycol) (PEG) is one of the most widely used polymers in pharmaceuticals and personal care applications, playing a key role as a surfactant, emulsifier, and in drug delivery systems by improving solubility and extending circulation time. However, standard PEG is typically polydisperse, consisting of mixtures of different chain lengths that can introduce variability in analysis, reproducibility, and formulation performance.
https://www.chemistryworld.com/industry/advantages-of-monodisperse-peg-in-drug-development/4023224.article